Current SPARK TEL AVIV Projects

Current SPARK TEL AVIV Projects. Photo by National Cancer Institute on Unsplash


Team	Title	Indication / Research Area	Modality
2024-2025
1	ConSurf - an Evolutionary Flashlight for Detecting Functional Regions in Proteins, DNA and RNA Prof. Nir Ben-Tal Visit the project page >>	Bioinformatics	Technological

2	Gradient Boosted Trees on Complex Data Types Prof. Ran Gilad-Bacharch Visit the project page >>	Bioinformatics	Technological

3	An Algorithm for Clustering Biological Networks Prof. Roded Sharan Visit the project page >>	Bioinformatics	Technological

4	Harnessing Drug Repurposing for Burn Treatment: Optimizing Cultured Epidermal Prof. Lihi Adler-Abramovich Visit the project page >>	Burn Reconstruction	Small Molecules Repurposing

2022-2023
5	Small RNAs as early predictors for preeclampsia. Prof. Noam Shomrom Visit the project page >>	Gynecology	Diagnostic

6	Repurposing of non-oncology drugs for the treatment of brain tumors. Prof. Lior Mayo Visit the project page >>	Oncology	Small Molecules Repurposing

7	Leveraging gene panel sequencing data for mutational signature analysis with applications to personalized treatment. Prof. Roded Sharan Visit the project page >>	Oncology	Diagnostic

2020-2021
8	miR126-5P for treating Motor Neuron Disease Prof. Eran Perelson Prof. Amir Dori Visit the project page >>	Rare/Orphane Diease Psychiatry Neurology	Gene Therapy

9	eBiopsy of skin - molecular harvesting with electroporation for rapid and minimally invasive diagnostic of basal cell carcinoma Prof. Alex Golberg Visit the project page >>	Oncology	Diagnostic Device

10	Creation of medication to treat optic nerve assault: NAION Prof. Itai Benhar Visit the project page >>	Opthamology	Biologicאנ

11	PERK modulation for Huntington’s disease therapy Prof. Gerardo Lederkramer Visit the project page >>	Rare/Orphane Diease Psychiatry Neurology	Small Molecules

2019-2020
12	Targeting cancer glycosylation with CAR-T cells for therapyresponses Prof. Vered Padler-Karavani Visit the project page >>	Oncology	Gene/Cell Therapy

13	Synthetic 9-cis ß-carotene for treatment of retinal degeneration Prof. Ehud Gazit Visit the project page >>	Opthamology	Small Molecules

14	Screening assay for early detection of ovarian cancer in BRCA-mutation carriers Prof. Keren Levanon Prof. Tami Gaiger Visit the project page >>	Gynecology	Diagnostic

15	Exploring the effectiveness of novel treatment targeting myelination deficits on Williams Syndrome clinical symptoms Prof. Boaz Barak Visit the project page >>	Rare/Orphane Diease Psychiatry Neurology	Small Molecules Repurposing

2018-2019
16	Preventing post-surgical colorectal cancer metastases: A novel approach based on perioperative pharmacological blockade of stress-inflammatory responses Prof. Shamgar Ben-Eliyahu Visit the project page >>	Gastroenthrology	Small Molecules Repurposing

17	Improved EHDV-TAU oncolytic virotherapy Prof. Eran Bacharach Visit the project page >>	Oncology	Biologic

18	Restoring the Function of APC in Colorectal Cancer Syndromes Prof. Rina Rosin-Arbesfeld Visit the project page >>	Gastroenthrology	Small Molecules Repurposing

19	Novel pharmacological approach for treating glycogen storage disorders Prof. Miguel Weil Visit the project page >>	Rare/Orphane Disease Metabolic	Small Molecules