Current SPARK TEL AVIV Projects

Current SPARK TEL AVIV Projects. Photo by National Cancer Institute on Unsplash


Team	Title	Indication / Research Area	Modality
2024-2025
1	ConSurf - an evolutionary flashlight for detecting functional regions in proteins, DNA and RNA	Bioinformatics	Technological
2	Gradient Boosted Trees on Complex Data Types	Bioinformatics	Technological
3	An algorithm for clustering biological networks	Bioinformatics	Technological
4	Harnessing drug repurposing for burn treatment: Optimizing cultured epidermal	Burn Reconstruction	Small molecules Repurposing
2022-2023
5	Small RNAs as early predictors for preeclampsia.	Gynecology	Diagnostic
6	Repurposing of non-oncology drugs for the treatment of brain tumors.	Oncology	Therapeutic
7	Leveraging gene panel sequencing data for mutational signature analysis with applications to personalized treatment.	Oncology	Diagnostic
2020-2021
8	miR126-5P for treating Motor Neuron Disease Visit the project page >>	Rare/Orphane Diease Psychiatry Neurology	Gene Therapy
9	eBiopsy of skin - molecular harvesting with electroporation for rapid and minimally invasive diagnostic of basal cell carcinomaVisit the project page >>	Oncology	Diagnostic Device
10	Creation of medication to treat optic nerve assault: NAION Visit the project page >>	Opthamology	Biologic
11	PERK modulation for Huntington’s disease therapy Visit the project page >>	Rare/Orphane Diease Psychiatry Neurology	Small Molecules
2019-2020
12	Targeting cancer glycosylation with CAR-T cells for therapyresponses Visit the project page >>	Oncology	Gene/Cell Therapy
13	Synthetic 9-cis ß-carotene for treatment of retinal degenerationVisit the project page >>	Opthamology	Small Molecules
14	Screening assay for early detection of ovarian cancer in BRCA-mutation carriers	Gnycology	Diagnostic
15	Exploring the effectiveness of novel treatment targeting myelination deficits on Williams Syndrome clinical symptoms	Rare/Orphane Diease Psychiatry Neurology	Small Molecules Repurposing
2018-2019
16	Preventing post-surgical colorectal cancer metastases: A novel approach based on perioperative pharmacological blockade of stress-inflammatory responses Visit the project page >>	Gastroenthrology	Small Molecules Repurposing
17	Improved EHDV-TAU oncolytic virotherapy Visit the project page >>	Oncology	Biologic
18	Restoring the Function of APC in Colorectal Cancer Syndromes Visit the project page >>	Gastroenthrology	Small Molecules Repurposing
19	Novel pharmacological approach for treating glycogen storage disorders Visit the project page >>	Rare/Orphane Disease Metabolic	Small Molecules